The most important objective of this book is to serve as a guide to undergraduate, postgraduate students and researchers in using SPSS and G*Power software in their various applied researches, especially in health research area. Almost all applied researches need a basic, moderate and advanced statistical analysis in their research project. This book provides sample size calculations required according to the study design and step-by-step analysis using SPSS as well as the result presentation for obtained output. This book aims to assist students in making good presentations and conclusions based on the results obtained and provides valuable information in statistical methods in applied research.